(S)-N-(2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide

• Catalog: OFC1448440525
• CAS: 1448440-52-5
• Category: Fluorinated Amides
• Synonyms: SP-13786
• Purity: 97%
• MDL Number: MFCD29477499

• Molecular Formula: C17H14F2N4O2
• Molecular Weight: 344.32
• Molar Refractivity: 88.37

• Bioavailability Score: 0.55
• Egan: 0.0
• Ghose: None
• Lipinski: 0.0
• Muegge: 0.0
• Veber: 0.0
• Consensus LogP: 1.61
• MLogP: 0.79
• SILICOS-IT: 2.14
• WLogP: 2.18
• XLogP3: 1.62
• iLogP: 1.33
• BBB Permeant: No
• CYP1A2 Inhibitor: No
• CYP2C19 Inhibitor: Yes
• CYP2C9 Inhibitor: No
• CYP2D6 Inhibitor: No
• CYP3A4 Inhibitor: No
• GI Absorption: High
• LogKp: -7.25 cm/s
• P-gp Substrate: No
• Fraction Csp3: 0.29

• GHS Pictogram: GHS07
• Hazard Statements: H302-H315-H319-H335
• Precautionary Statements: P261-P305+P351+P338