(S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide hydrochloride(1:x)

• Catalog: OFC1254955219
• CAS: 1254955-21-9
• Category: Fluoroalkenes
• Purity: 97%
• MDL Number: MFCD30342454

• Molecular Formula: C24H26Cl2FN5O3
• Molecular Weight: 522.40
• Molar Refractivity: 136.86

• Bioavailability Score: 0.55
• Egan: 0.0
• Ghose: None
• Lipinski: 1.0
• Muegge: 0.0
• Veber: 0.0
• Consensus LogP: 3.32
• MLogP: 2.91
• SILICOS-IT: 3.82
• WLogP: 5.42
• XLogP3: 4.44
• iLogP: 0.0
• BBB Permeant: No
• CYP1A2 Inhibitor: No
• CYP2C19 Inhibitor: Yes
• CYP2C9 Inhibitor: Yes
• CYP2D6 Inhibitor: Yes
• CYP3A4 Inhibitor: Yes
• GI Absorption: High
• LogKp: -6.33 cm/s
• P-gp Substrate: Yes
• Fraction Csp3: 0.29

• GHS Pictogram: GHS07
• Hazard Statements: H302-H315-H319-H335
• Precautionary Statements: P261-P305+P351+P338