N-(3-(2-((2,3-Difluoro-4-(4-(2-hydroxyethyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide

• Catalog: OFC1660963427
• CAS: 1660963-42-7
• Category: Fluorinated Aromatic Alcohols and Phenols
• Purity: 97%
• MDL Number: MFCD30345533

• Molecular Formula: C29H28F2N6O2
• Molecular Weight: 530.57
• Molar Refractivity: 155.31

• Bioavailability Score: 0.55
• Egan: 0.0
• Ghose: None
• Lipinski: 1.0
• Muegge: 0.0
• Veber: 0.0
• Consensus LogP: 4.01
• MLogP: 3.11
• SILICOS-IT: 4.36
• WLogP: 4.45
• XLogP3: 4.26
• iLogP: 3.89
• BBB Permeant: No
• CYP1A2 Inhibitor: No
• CYP2C19 Inhibitor: Yes
• CYP2C9 Inhibitor: Yes
• CYP2D6 Inhibitor: Yes
• CYP3A4 Inhibitor: Yes
• GI Absorption: High
• LogKp: -6.51 cm/s
• P-gp Substrate: Yes
• Fraction Csp3: 0.21

• GHS Pictogram: GHS07
• Hazard Statements: H302-H315-H319-H335
• Precautionary Statements: P261-P305+P351+P338