N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)thio)-2-hydroxy-2-methylpropanamide

• Catalog: OFC90356788
• CAS: 90356-78-8
• Category: Fluorinated Nitriles
• Purity: 97%
• MDL Number: MFCD08235143

• Molecular Formula: C18H14F4N2O2S
• Molecular Weight: 398.37
• Molar Refractivity: 92.49

• Bioavailability Score: 0.55
• Egan: 0.0
• Ghose: None
• Lipinski: 0.0
• Muegge: 0.0
• Veber: 0.0
• Consensus LogP: 3.94
• MLogP: 3.45
• SILICOS-IT: 4.44
• WLogP: 5.58
• XLogP3: 3.58
• iLogP: 2.65
• BBB Permeant: No
• CYP1A2 Inhibitor: Yes
• CYP2C19 Inhibitor: Yes
• CYP2C9 Inhibitor: No
• CYP2D6 Inhibitor: Yes
• CYP3A4 Inhibitor: Yes
• GI Absorption: High
• LogKp: -6.19 cm/s
• P-gp Substrate: No
• Fraction Csp3: 0.22