Nicotinamide

• Catalog Number: ACM98920-1
• Product Name: Nicotinamide
• CAS: 98-92-0
• Category: Inhibitors
• Description: Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity.
• Synonyms: Aminicotin
• IUPAC Name: Pyridine-3-carboxamide
• Molecular Weight: 122.12
• Molecular Formula: C6H6N2O
• Canonical SMILES: C1=CC(=CN=C1)C(=O)N
• InChI: InChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
• InChI Key: DFPAKSUCGFBDDF-UHFFFAOYSA-N
• Boiling Point: 150-160 °C
• Melting Point: 128-131 °C(lit.)
• Flash Point: 182 °C
• Density: 1.40 g/cm³
• Solubility: Soluble in butanol, chloroform
• Appearance: White powder
• Storage: 2-8 °C
• Complexity: 114
• EC Number: 202-713-4
• Exact Mass: 122.048012819
• Hazard Statements: Xi,T,F
• Monoisotopic Mass: 122.048012819
• pKa: 3.3(at 20 °C)
• Refractive Index: 1.4660
• Safety Description: 26-36-37/39-45-36/37-16-7
• Supplemental Hazard Statements: H315-H319-H335-H225-H301+H311+H331-H370
• Symbol: GHS07,GHS02,GHS06,GHS08
• Topological Polar Surface Area: 56 Ų

Custom Q&A

What is the molecular formula of Nicotinamide?

The molecular formula of Nicotinamide is C6H6N2O.

What are some synonyms for Nicotinamide?

Some synonyms for Nicotinamide are niacinamide, 3-Pyridinecarboxamide, and Nicotinic acid amide.

What is the molecular weight of Nicotinamide?

The molecular weight of Nicotinamide is 122.12 g/mol.

When was Nicotinamide created and modified?

Nicotinamide was created on September 16, 2004, and modified on October 21, 2023.

What is the primary significance of Nicotinamide?

The primary significance of Nicotinamide is in the prevention and/or cure of blacktongue and pellagra.

What are some functions of Nicotinamide?

Nicotinamide functions as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor, a metabolite, a cofactor, an antioxidant, a neuroprotective agent, an EC 3.5.1.98 (histone deacetylase) inhibitor, an anti-inflammatory agent, a Sir2 inhibitor, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a mouse metabolite, a human urinary metabolite, and a geroprotector.

What is the IUPAC name of Nicotinamide?

The IUPAC name of Nicotinamide is pyridine-3-carboxamide.

What is the InChI of Nicotinamide?

The InChI of Nicotinamide is InChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9).

What is the InChIKey of Nicotinamide?

The InChIKey of Nicotinamide is DFPAKSUCGFBDDF-UHFFFAOYSA-N.

What is the CAS number of Nicotinamide?

The CAS number of Nicotinamide is 98-92-0.