N-Bromosuccinimide (NBS)

• CAS: 128-08-5
• Catalog Number: ACM128085
• Category: Bromine Series

Custom Q&A

What is the molecular formula of N-bromosuccinimide?

The molecular formula of N-bromosuccinimide is C4H4BrNO2.

What are some synonyms for N-bromosuccinimide?

Some synonyms for N-bromosuccinimide include 1-Bromopyrrolidine-2,5-dione, Succinbromimide, and Succinbromide.

How is N-bromosuccinimide described in the reference?

N-bromosuccinimide is described as a five-membered cyclic dicarboximide compound having a bromo substituent on the nitrogen atom, with a role as a reagent.

What is the molecular weight of N-bromosuccinimide?

The molecular weight of N-bromosuccinimide is 177.98 g/mol.

How is N-bromosuccinimide used in chemical synthesis?

N-bromosuccinimide is used in a variety of bromination reactions for chemical synthesis, such as donating bromine to alkenes, allylic or benzyl compounds, carbonyl-containing compounds, and aromatic compounds like phenols and anilines.

What is the InChIKey for N-bromosuccinimide?

The InChIKey for N-bromosuccinimide is PCLIMKBDDGJMGD-UHFFFAOYSA-N.

What is the Canonical SMILES representation of N-bromosuccinimide?

The Canonical SMILES representation of N-bromosuccinimide is C1CC(=O)N(C1=O)Br.

How is N-bromosuccinimide used as a protein modification agent?

N-bromosuccinimide can be used as a protein modification agent that targets tryptophan and histidine residues.

How does N-bromosuccinimide decompose over time?

N-bromosuccinimide will decompose over time and give off bromine.

What are some properties of N-bromosuccinimide mentioned in the reference?

Some properties of N-bromosuccinimide mentioned include its molecular weight, XLogP3-AA value, hydrogen bond donor count, hydrogen bond acceptor count, rotatable bond count, and exact mass.

Synthetic Use

Downstream Synthesis Route 1

• 188290-36-0
• 128-08-5

• 1003-09-4

Reference: [1] Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical & Analytical, 1988, vol. 27, # 6, p. 538 - 539

Downstream Synthesis Route 2

• 56-23-5
• 128-08-5
• 616-44-4

• 14282-76-9

Reference: [1] Journal of the American Chemical Society, 1951, vol. 73, p. 4018
[2] Journal of the American Chemical Society, 1949, vol. 71, p. 1201,1203

Downstream Synthesis Route 3

• 128-08-5
• 616-44-4

• 14282-76-9

Reference: [1] Patent: EP308170, 1989, A1,

Downstream Synthesis Route 4

• 16198-01-9
• 56-23-5
• 128-08-5
• 94-36-0

• 528-58-5

Reference: [1]Proceedings - Indian Academy of Sciences, Section A,1957,p. 25,27

Downstream Synthesis Route 5

• 56-23-5
• 42602-67-5
• 128-08-5

• 106944-15-4

Reference: [1]Nippon Kagaku Zasshi,1957,vol. 78,p. 779,783
Chem.Abstr.,1960,p. 22559

Downstream Synthesis Route 6

• 42602-67-5
• 128-08-5
• 67-66-3

• 106944-15-4

Reference: [1]Journal of the American Chemical Society,1954,vol. 76,p. 2447,2449

* For details of the synthesis route, please refer to the original source to ensure accuracy.