fenbendazole

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Catalog Number
ACM43210679
Product Name
fenbendazole
Structure
Structure
CAS
43210-67-9
Category
Inhibitors
Description
Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53.
Molecular Weight
299.34
Molecular Formula
C15H13N3O2S
Canonical SMILES
O=C(OC)NC1=NC2=CC=C(SC3=CC=CC=C3)C=C2N1
Melting Point
233°C
Density
1.4 g/cm³
Appearance
White to pale yellow powder
Storage
Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
Shipping
Can be shipped at room temperature, where not in use may vary.
Please kindly note that our products are for research use only.

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