Estradiol benzoate

• Catalog Number: ACM50500
• Product Name: Estradiol benzoate
• CAS: 50-50-0
• Category: Steroidal Compounds
• Synonyms: folone; EBZ; Estradiolbenzoate; diogynb; ODB; ESTON-B; β-Estradiol 3-benzoate; Solestro; 17beta-estradiol 3-benzoate; Graafina; Estradiol benzoate; Estradiol Benzoate; MEE
• IUPAC Name: [(8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl]benzoate
• Molecular Weight: 376.49
• Molecular Formula: C₂₅H₂₈O₃
• Canonical SMILES: CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)OC(=O)C5=CC=CC=C5
• InChI Key: UYIFTLBWAOGQBI-BZDYCCQFSA-N
• Boiling Point: 531.2ºC at 760mmHg
• Melting Point: 191-198ºC
• Flash Point: 212ºC
• Density: 1.185g/cm³
• EC Number: 200-043-7
• Exact Mass: 376.20400
• Hazard Statements: T:Toxic
• Safety Description: S53-S22-S36/37/39-S45
• WGK Germany: 3

Custom Q&A

What is the molecular formula of estradiol benzoate?

The molecular formula is C25H28O3.

What is the molecular weight of estradiol benzoate?

The molecular weight is 376.5 g/mol.

What is the role of estradiol benzoate?

Estradiol benzoate has a role as a xenoestrogen and an estrogen receptor agonist.

What is estradiol benzoate a pro-drug ester of?

Estradiol benzoate is a pro-drug ester of estradiol.

What are the synonyms of estradiol benzoate?

The synonyms are estradiol benzoate, Benovocylin, Oestradiol benzoate, Benzhormovarine, and more.

What are the downstream effects of estradiol benzoate within the body?

Estradiol benzoate binds to the Estrogen Receptor (ER) and has downstream effects in various tissues, including the breasts, uterus, ovaries, skin, prostate, bone, fat, and brain.

Why is estradiol benzoate commonly produced with an ester side-chain?

Endogenous estradiol has low oral bioavailability on its own, so esterification of estradiol improves absorption and bioavailability after oral administration or sustains release from depot intramuscular injections.

Is estradiol benzoate currently available in Canada or the US?

No, estradiol benzoate is not currently available in Canada or the US.

What are the computed descriptors for estradiol benzoate?

The computed descriptors include the IUPAC name, InChI, InChIKey, Canonical SMILES, and Isomeric SMILES.

What is the CAS number of estradiol benzoate?

The CAS number is 50-50-0.