Roflumilast-d3

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Catalog Number
ACM1189992004
Product Name
Roflumilast-d3
Structure
Structure
CAS
1189992-00-4
Category
Inhibitors
Description
Roflumilast-d3 is deuterium labeled Roflumilast. Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells.
Synonyms
3-(Cyclopropylmethoxy-d3)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide; B 9302-107-d3; BY 217-d3; BYK 20869-d3;
Molecular Weight
406.23
Molecular Formula
C17H11D3Cl2F2N2O3
Canonical SMILES
[2H]C1(CC1)C([2H])([2H])OC2=C(C=CC(C(NC3=C(Cl)C=NC=C3Cl)=O)=C2)OC(F)F
Appearance
Crystallin Solid
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping
Can be shipped at room temperature, where not in use may vary.
MSDS
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COA
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Spec Sheet
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