Structure

7-Chloro-1-(2,4-difluoro-phenyl)-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester

CAS
100491-29-0
Catalog Number
ACM100491290
Category
Other Products
Molecular Weight
382.72
Molecular Formula
C17H10ClF3N2O3

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  • Product Description
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Specification

Synonyms
7-Chloro-1-(2,4-difluoro-phenyl)-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester;Ethyl 1-(2,4-difluorophenyl)-7-cl-6-f-4-o-hydropyridino[2,3-b]pyridine-3-carboxylate
Density
1.523g/cm³
Physical Description
Ethyl 1-(2,4-difluorophenyl)-7-Cl-6-F-4-O-hydropyridino[2,3-b]pyridine-3-carboxylate 99% (5g)

Upstream Synthesis Route 1

  • 105152-47-4
  • 100491-29-0

Reference: [1] Patent: US4704459, 1987, A,

Upstream Synthesis Route 2

  • 100490-99-1
  • 100491-29-0

Reference: [1] Journal of Medicinal Chemistry, 1986, vol. 29, # 11, p. 2364 - 2369
[2] Journal of Medicinal Chemistry, 1992, vol. 35, # 3, p. 518 - 525
[3] Patent: US2014/73631, 2014, A1, . Location in patent: Paragraph 0128; 0133

Upstream Synthesis Route 3

  • 96568-04-6
  • 100491-29-0

Reference: [1] Journal of Medicinal Chemistry, 1986, vol. 29, # 11, p. 2364 - 2369
[2] Journal of Medicinal Chemistry, 1992, vol. 35, # 3, p. 518 - 525
[3] Patent: US2014/73631, 2014, A1,

Downstream Synthesis Route 1

  • 110-85-0
  • 100491-29-0
  • 104051-62-9

Reference: [1]Journal of Medicinal Chemistry,1986,vol. 29,p. 2364 - 2369
[2]Patent: WO2005/70940,2005,A2 .Location in patent: Page/Page column 38

Downstream Synthesis Route 2

  • 109-01-3
  • 100491-29-0
  • 100492-07-7

Reference: [1]Journal of Medicinal Chemistry,1986,vol. 29,p. 2364 - 2369

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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