What is the molecular formula of bortezomib?
The molecular formula of bortezomib is C19H25BN4O4.
What are some synonyms for bortezomib?
Some synonyms for bortezomib are Velcade, PS-341, and Bortezomib (PS-341).
What is the molecular weight of bortezomib?
The molecular weight of bortezomib is 384.2 g/mol.
What is the role of bortezomib?
Bortezomib has a role as an antineoplastic agent, a proteasome inhibitor, a protease inhibitor, and an antiprotozoal drug.
When was bortezomib first synthesized?
Bortezomib was first synthesized in 1995.
What is the mechanism of action of bortezomib as?
The mechanism of action of bortezomib is as a Proteasome Inhibitor.
When did bortezomib become the first anticancer proteasome inhibitor approved by the FDA?
Bortezomib became the first anticancer proteasome inhibitor approved by the FDA in May 2003.
What type of clinical trials are ongoing to investigate the therapeutic efficacy of bortezomib?
Phase I, II, III, and IV clinical trials are ongoing to investigate the therapeutic efficacy of bortezomib in leukemia, myasthenia gravis, systemic lupus erythematosus, rheumatoid arthritis, and solid tumors.
What is the IUPAC name of bortezomib?
The IUPAC name of bortezomib is [(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid.
What is the InChIKey of bortezomib as?
The InChIKey of bortezomib is GXJABQQUPOEUTA-RDJZCZTQSA-N.