Arbutin

• Catalog Number: ACM497767
• Product Name: Arbutin
• CAS: 497-76-7
• Category: Material of cosmetics
• Description: Arbutin is a natural active substance derived from green plants. It combines the "green plant, safe and reliable" and "high-efficiency discoloration" into a skin decolorizing component, which can quickly penetrate into the skin without affecting cell proliferation. At the same time, it can effectively inhibit the activity of tyrosinase in the skin, block the formation of melanin, and directly combine with tyrosinase to accelerate the decompositio;n and excretion of melanin, thereby reducing skin pigmentation, eliminating pigmentation and Freckles, and do not produce toxic, irritating, sensitizing and other side effects on melanocytes, as well as bactericidal and anti-inflammatory effects.
• Synonyms: 4-Hydroxyphenyl-beta-D-glucopyranosid
• IUPAC Name: (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol
• Molecular Weight: 272.25
• Molecular Formula: C12H16O7
• Canonical SMILES: C1=CC(=CC=C1O)OC2C(C(C(C(O2)CO)O)O)O
• InChI: InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1
• InChI Key: BJRNKVDFDLYUGJ-RMPHRYRLSA-N
• Boiling Point: 375.31 °C
• Melting Point: 195-198 °C
• Flash Point: 293.4 °C
• Density: 1.3582 g/cm³
• Solubility: Soluble in water, alcohol
• Appearance: Solid
• Storage: Inert atmosphere, room temperature
• Assay: 0.99
• Complexity: 279
• EC Number: 207-850-3
• Exact Mass: 272.08960285
• Isomeric SMILES: C1=CC(=CC=C1O)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O
• MDL Number: MFCD00016915
• Monoisotopic Mass: 272.08960285
• Packaging: 1 kg
• Physical State: Solid
• pKa: 10.10±0.15(Predicted)
• Plant Origin: leaf ot bearberry
• Refractive Index: -65.5 ° (C=4, H₂O)
• Stability: Stable. Hygroscopic - store under dry nitrogen.
• Topological Polar Surface Area: 120 Ų