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Arbekacin

Catalog Number
ACM51025855
Product Name
Arbekacin
Structure
CAS Number
51025-85-5
Synonyms
ARBEKACIN;(s)-oxy-1-oxobutyl)-2-deoxy;3,4,6-tetradeoxy-alpha-d-erythro-hexopyranosyl-(1-4))-n(sup1)-(4-amino-2-hydr;habekacin;haberacin;1665RB;1-N-[(S)-4-Amino-2-hydroxybutyryl]-3,4-dideoxykanamycin B;AHB-DKB
Molecular Weight
552.62
Molecular Formula
C22H44N6O10
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1Detecting 16S rRNA Methyltransferases in Enterobacteriaceae by Use of Arbekacin

McGann P, Chahine S, Okafor D, et al.

Journal of clinical microbiology, 2016, 54(1): 208-211.

16S rRNA methyltransferases confer resistance to most aminoglycosides, but discriminating their activity from that of aminoglycoside-modifying enzymes (AMEs) is challenging using phenotypic methods. The authors demonstrate that arbekacin, an aminoglycoside refractory to most AMEs, can rapidly detect 16S methyltransferase activity in Enterobacteriaceae with high specificity using the standard disk susceptibility test.

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Contact us

Email:
Tel:1-201-478-8534
1-516-662-5404
Fax: 1-516-927-0118
Address: 2200 Smithtown Avenue, Room 1 Ronkonkoma, NY 11779-7329 USA