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Home > Product > Organic Building Blocks > Organic Silicon Compounds > Alkyl Silane > 2-(Trimethylsilyl)ethoxymethyl chloride

2-(Trimethylsilyl)ethoxymethyl chloride

Catalog Number
ACM76513694
Product Name
2-(Trimethylsilyl)ethoxymethyl chloride
Structure
CAS Number
76513-69-4
EC Number
278-483-4
IUPAC Name
2-(chloromethoxy)ethyl-trimethylsilane
Synonyms
2-(chloromethoxy)ethyl-trimethylsilane;
Category
Ether base silane
Molecular Weight
166.72
Exact Mass
166.05800
Molecular Formula
C6H15ClOSi
Boiling Point
170-172ºC
Flash Point
46ºC
Density
0.942
Purity
95%+
Appearance
Transparent liquid
SMILES
C[Si](C)(C)CCOCCl
InChIKey
BPXKZEMBEZGUAH-UHFFFAOYSA-N
Safty Description
S16-S26-S36/37/39-S45
Hazard Statements
C:Corrosive;
WGK Germany
3
Stability
Stable under normal temperatures and pressures.
Packing Group
III
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1Pyrimidine acyclic nucleosides, 1-[(2-Hydroxyethoxy)methyl]pyrimidines as candidate antivirals.

Kelley JL, Kelsey JE, Hall WR, Krochmal MP, Schaeffer HJ.

J Med Chem. 1981 Jun;24(6):753-6.

A number of pyrimidine acyclic nucleosides were synthesized and tested for activity against herpes simplex virus type 1. Synthesis of 1-[(2-hydroxyethoxy)methyl]cytosine (8) and 1-[(2-hydroxyethoxy)methyl]uracil (14) was accomplished in two or three steps from 2,4-diethoxypyrimidine and 2-(benzoyloxy)ethoxymethyl chloride. The 5-methyl (20), 5-(trifluoromethyl) (21), and 5-fluoro (22) analogues of 14 were available in two steps form the appropriate bis(trimethylsilyl)ated 5-substituted uracil and 2-(acetoxymethoxy)ethyl acetate or 2-(benzoyloxy)ethoxymethyl chloride. Read More

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Tel:1-201-478-8534
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Address: 2200 Smithtown Avenue, Room 1 Ronkonkoma, NY 11779-7329 USA