Schweikl H1, Schmalz G, Weinmann W.
Mutat Res. 2002 Nov 26;521(1-2):19-27.Ring-opening molecules like oxiranes (epoxides) maybe suitable for the development of non-shrinking dental composite materials. Since oxiranes are reactive molecules, they can cause adverse biological effects in living organisms. The introduction of siloranes, a merger of silane and oxirane, may solve this problem. Here, new oxiranes and siloranes were analyzed for the induction of mutations in Salmonella typhimurium (TA97a, TA98, TA100, and TA102), and a reactive oxirane molecule served as a reference. Read More