6-Bromo-4-chlorocinnoline

• CAS: 68211-15-4
• Catalog Number: ACM68211154
• Category: Bromine Series
• Molecular Weight: 243.49
• Molecular Formula: C₈H₄BrClN₂

Synthetic Use

Upstream Synthesis Route 1

• 876-88-0

• 68211-15-4

Reference: [1] Patent: JP6378918, 2018, B2, . Location in patent: Paragraph 0721; 0724

Upstream Synthesis Route 2

• 876-88-0

• 68211-15-4

Reference: [1] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 4, p. 434 - 438

Upstream Synthesis Route 3

• 29124-56-9

• 68211-15-4

Reference: [1]Woods, Keith W.; Fischer, John P.; Claiborne, Akiyo; Li, Tongmei; Thomas, Sheela A.; Zhu, Gui-Dong; Diebold, Robert B.; Liu, Xuesong; Shi, Yan; Klinghofer, Vered; Han, Edward K.; Guan, Ran; Magnone, Shayna R.; Johnson, Eric F.; Bouska, Jennifer J.; Olson, Amanda M.; Jong, Ron de; Oltersdorf, Tilman; Luo, Yan; Rosenberg, Saul H.; Giranda, Vincent L.; Li, Qun
[Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 20, p. 6832 - 6846]
[2]Leonard; Boyd
[Journal of Organic Chemistry, 1946, vol. 11, p. 405,412]
[3]Current Patent Assignee: UNIVERSITY SYSTEM OF GEORGIA - US2015/259331, 2015, A1
[4]Current Patent Assignee: FUDAN UNIVERSITY - CN112876456, 2021, A
[5]Chen, Yi; Deng, Mingli; Jia, Yu; Ling, Yun; Liu, Xiaofeng; Lu, Mingzhu; Tian, Chengze; Wu, Tianze; Yang, Chengbin; Yang, Yongtai; Zhou, Yaming
[Bioorganic and Medicinal Chemistry Letters, 2021, vol. 48]

Upstream Synthesis Route 4

• 5234-26-4

• 68211-15-4

Reference: [1]Bioorganic and Medicinal Chemistry,2006,vol. 14,p. 6832 - 6846
[2]ACS Medicinal Chemistry Letters,2015,vol. 6,p. 434 - 438
[3]Patent: JP6378918,2018,B2

Downstream Synthesis Route 1

• 68211-15-4

• 318276-72-1

Reference: [1] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 20, p. 6832 - 6846
[2] Journal of the Chemical Society, 1950, p. 392,395

Downstream Synthesis Route 2

• 68211-15-4

• 318276-72-1

Reference: [1]Bioorganic and Medicinal Chemistry,2006,vol. 14,p. 6832 - 6846
[2]Journal of the Chemical Society,1950,p. 392,395

* For details of the synthesis route, please refer to the original source to ensure accuracy.