Yin Q1,2, Wang L3, Sun C1.
Rapid Commun Mass Spectrom. 2016 Aug;30 Suppl 1:155-61. doi: 10.1002/rcm.7618.RATIONALE: Miglitol (1) derived from 1-deoxynojirimycin is an iminosugar that is useful in the treatment of type 2 diabetes mellitus. Isomers (2, 3, 4) that differ at the C2 and C3 positions of hydroxyl groups from miglitol are impurities resulting from the synthesis of miglitol. The impurity profile of a drug substance is critical to its safety assessment and is important for monitoring the manufacturing process. Read More