2-Ethynyl-α,α,α-trifluorotoluene

• CAS: 704-41-6
• Catalog Number: ACM704416
• Category: Alkynyl
• Molecular Weight: 170.13
• Hazard Statements: H302
• RIDADR: NONH for all modes of transport
• Symbol: GHS07

Synthetic Use

Upstream Synthesis Route 1

• 40230-94-2

• 704-41-6

Reference: [1]Journal of the American Chemical Society,2005,vol. 127,p. 4599 - 4608
[2]Tetrahedron Letters,1972,vol. 13,p. 5209 - 5212
[3]Patent: WO2016/55947,2016,A1 .Location in patent: Page/Page column 57; 125
[4]Organic Letters,2019,vol. 21,p. 10057 - 10062

Downstream Synthesis Route 1

• 704-41-6

• 17408-14-9

Reference: [1] Journal of the American Chemical Society, 2011, vol. 133, # 30, p. 11632 - 11640
[2] Applied Organometallic Chemistry, 2012, vol. 26, # 12, p. 722 - 726
[3] Chinese Journal of Chemistry, 2014, vol. 32, # 10, p. 1072 - 1076
[4] Journal of Molecular Catalysis A: Chemical, 2011, vol. 336, # 1-2, p. 1 - 7

Downstream Synthesis Route 2

• 704-41-6
• 73183-34-3

• 1294009-25-8

Reference: [1] Chemical Communications, 2014, vol. 50, # 16, p. 2058 - 2060
[2] Journal of the American Chemical Society, 2011, vol. 133, # 20, p. 7859 - 7871

Downstream Synthesis Route 3

• 704-41-6
• 25015-63-8

• 1294009-25-8

Reference: [1] Chemical Communications, 2018, vol. 54, # 97, p. 13690 - 13693
[2] Angewandte Chemie - International Edition, 2018, vol. 57, # 9, p. 2334 - 2338[3] Angew. Chem., 2018, vol. 130, p. 2358 - 2362,5

Downstream Synthesis Route 4

• 591-50-4
• 704-41-6

• 147344-86-3

Reference: [1]Synlett,2005,p. 619 - 622
[2]Chemistry - A European Journal,2008,vol. 14,p. 6994 - 6999
[3]Beilstein Journal of Organic Chemistry,2016,vol. 12,p. 2005 - 2011
[4]Green Chemistry,2015,vol. 17,p. 1071 - 1076

* For details of the synthesis route, please refer to the original source to ensure accuracy.