2,4,5-Trifluorobenzoyl chloride

• CAS: 88419-56-1
• Catalog Number: ACM88419561
• Category: Aryl Fluorinated Building Blocks
• Molecular Weight: 194.54
• Hazard Statements: H302 + H312 + H332-H315-H319-H335
• RIDADR: NONH for all modes of transport
• Symbol: GHS07

Synthetic Use

Upstream Synthesis Route 1

• 446-17-3

• 88419-56-1

Reference: [1]Journal of Medicinal Chemistry,2009,vol. 52,p. 7954 - 7957

Downstream Synthesis Route 1

• 67-56-1
• 88419-56-1

• 20372-66-1

Reference: [1] Heterocycles, 1996, vol. 43, # 8, p. 1719 - 1734

Downstream Synthesis Route 2

• 1071-46-1
• 88419-56-1

• 98349-24-7

Reference: [1] Journal of Medicinal Chemistry, 1999, vol. 42, # 19, p. 3899 - 3909
[2] Patent: WO2008/36420, 2008, A2, . Location in patent: Page/Page column 45-46
[3] Journal of Medicinal Chemistry, 1991, vol. 34, # 1, p. 168 - 174

Downstream Synthesis Route 3

• 88419-56-1

• 93107-30-3

Reference: [1] Liebigs Annalen der Chemie, 1987, p. 29 - 37

Downstream Synthesis Route 4

• 1071-46-1
• 88419-56-1

• 98349-24-7

Reference: [1]Journal of Medicinal Chemistry,1999,vol. 42,p. 3899 - 3909
[2]Patent: WO2008/36420,2008,A2 .Location in patent: Page/Page column 45-46
[3]Journal of Medicinal Chemistry,1991,vol. 34,p. 168 - 174

Downstream Synthesis Route 5

• 88419-56-1
• 105-53-3

• 104600-15-9

Reference: [1]Grohe, Klaus; Heitzer, Helmut
[Liebigs Annalen der Chemie, 1987, p. 29 - 37]
[2]Current Patent Assignee: PFIZER INC - US4940710, 1990, A
[3]Current Patent Assignee: NANJING YIWEI PHARMACEUTICAL TECH - CN113929579, 2022, A
Location in patent: Paragraph 0006; 0019; 0024-0025

* For details of the synthesis route, please refer to the original source to ensure accuracy.