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Home > Product > (1Alpha,4alpha,6alpha)-(±)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-ol

(1Alpha,4alpha,6alpha)-(±)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-ol

Catalog Number
ACM60761004
Product Name
(1Alpha,4alpha,6alpha)-(±)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-ol
Structure
CAS Number
60761-00-4
EC Number
262-408-7
IUPAC Name
(1R,5S)-2,2,4-trimethyl-3-oxabicyclo[2.2.2]octan-5-ol
Synonyms
(1alpha,4alpha,6alpha)-(±)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-ol;(1α,4α,6α)-(±)-1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-6-ol;(1alpha,4alpha,6alpha)-(1)-1,3,3-Trimethyl-2-oxabicyclo(2.2.2)octan-6-ol;Einecs 262-408-7;2-alpha-Hydroxy-1,8-cineole;NSC 341366
Molecular Weight
0
Exact Mass
170.13100
Molecular Formula
C10H18O2
Purity
95+%
SMILES
CC1(C2CCC(O1)(C(C2)O)C)C
InChIKey
YVCUGZBVCHODNB-HHCGNCNQSA-N
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1Transient Receptor Potential Cation Channel Subfamily M Member 8 channels mediate the anti‐inflammatory effects of eucalyptol

Caceres A I, Liu B, Jabba S V, et al.

British journal of pharmacology, 2017, 174(9): 867-879.

BACKGROUND AND PURPOSE Eucalyptol (1,8-cineol), the major ingredient in the essential oil of eucalyptus leaves and other medicinal plants, has long been known for its anti-inflammatory properties. Eucalyptol interacts with the TRP cation channels among other targets, but it is unclear which of these mediates its anti-inflammatory effects. EXPERIMENTAL APPROACH Effects of eucalyptol were compared in wild-type and TRPM8 channel-deficient mice in two different models: footpad inflammation elicited by complete Freund’s adjuvant (CFA) and pulmonary inflammation following administration of LPS. Read More

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Tel:1-201-478-8534
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Fax: 1-516-927-0118
Address: 2200 Smithtown Avenue, Room 1 Ronkonkoma, NY 11779-7329 USA