Fedorov A1, Liu HJ1, Lo HK1, Copéret C1.
J Am Chem Soc. 2016 Dec 21;138(50):16502-16507. doi: 10.1021/jacs.6b10817. Epub 2016 Dec 7.Narrowly dispersed, silica-supported Cu nanoparticles (ca. 2 nm) prepared via surface organometallic chemistry from a mesityl complex [Cu5Mes5] are highly active for the hydrogenation of a broad range of alkynes. High-throughput experimentation allows for identifying the optimal ligand and reaction conditions to turn these supported Cu nanoparticles into highly chemo- and stereoselective catalysts for the preparation of Z-olefins (overall, 23 examples). Read More