Jeong JH1, Jo YN, Kim HJ, Jin DE, Kim DO, Heo HJ.
J Med Food. 2014 Jan;17(1):83-91. doi: 10.1089/jmf.2013.3023.To find a neuroactive compound with a potent inhibitory effect on acetylcholinesterase (AChE) and in vivo anti-amnesic activity from natural resources, we evaluated anthocyanins and nonanthocyanins from black soybean extract. Nonanthocyanins from black soybean extract were the most potent and dose-dependent AChE inhibitors. Intracellular reactive oxygen species accumulation resulting from H₂O₂ treatment was significantly decreased compared with cells treated with H₂O₂ only. Read More