Obregón-Mendoza MA1, Estévez-Carmona MM2, Hernández-Ortega S3, Soriano-García M4, Ramírez-Apan MT5, Orea L6, Pilotzi H7, Gnecco D8, Cassani J9, Enríquez RG10.
Molecules. 2016 Dec 29;22(1). pii: E33. doi: 10.3390/molecules22010033.Curcumin and its derivatives have been extensively studied for their remarkable medicinal properties, and their chemical synthesis has been an important step in the optimization of well-controlled laboratory production. A family of new compounds that mimic the structure of curcumin and curcuminoids, here named retro-curcuminoids (7-14), was synthesized and characterized using 1D ¹H- and 13C-NMR, IR, and mass spectrometry; the X-ray structure of 7, 8, 9, 10, 12, 13, and 14 are reported here for the first time. Read More