Kabir MS1, Lorenz M, Van Linn ML, Namjoshi OA, Ara S, Cook JM.
J Org Chem. 2010 Jun 4;75(11):3626-43. doi: 10.1021/jo1004179.cis-1,2-Cyclohexanediol (L3) has been shown to be an efficient and versatile bidentate O-donor ligand that provides a highly active Cu-catalytic system. It was more effective than diols such as trans-1,2-cyclohexanediol or ethylene glycol. This commercially available cis-1,2-cyclohexanediol ligand facilitated the Cu-catalyzed cross-coupling reactions of alkyl, aryl, or heterocyclic thiols with either alkyl, aryl, heterocyclic, or substituted vinyl halides. Read More