Aydın E1, Türkez H1, Hacımüftüoğlu F2, Tatar A3, Geyikoğlu F4.
J Biomed Mater Res A. 2016 Dec 28. doi: 10.1002/jbm.a.35994. [Epub ahead of print]Titanium nanoparticles (NPs) have very wide application areas such as paint, cosmetics, pharmaceuticals and biomedical applications. And, to translate these nanomaterials to the clinic and industrial domains, their safety needs to be verified, particularly in terms of genotoxicity and cytotoxicity. Therefore, in this study, we aimed to investigate of cytotoxicity and changes in gene expression profiles influenced by commonly titanium (as titanium carbide, titanium carbo-nitride, titanium (II) oxide, titanium (III) oxide, titanium (IV) oxide, titanium nitride, titanium silicon oxide) NPs in human alveolar epithelial (HPAEpiC) and pharynx (HPPC) cell lines in vitro since inhalation is an important pathway for exposure to these nanoparticles. Read More