Yang L1, da Rocha SR.
Mol Pharm. 2014 May 5;11(5):1459-70. doi: 10.1021/mp400630z. Epub 2014 Apr 18.Poly(amido amine) (PAMAM) dendrimers are promising nanocarriers in a wide range of biomedical applications including gene and drug delivery and as imaging agents. They have unique structural properties and are characterized by high size uniformity, low polydispersity, and a large number of modifiable surface groups. Drug-dendrimer systems are usually further modified through the conjugation of ligands in order to confer the carriers' specific characteristics designed to enhance their efficacy. Read More