Sperotto E1, van Klink GP, de Vries JG, van Koten G.
J Org Chem. 2008 Jul 18;73(14):5625-8. doi: 10.1021/jo800491k. Epub 2008 Jun 21.A protocol for the copper-catalyzed aryl-sulfur bond formation between aryl iodides and thiophenols is reported. The reaction is catalyzed by a low amount (1-2.5 mol %) of readily available and ligand-free copper iodide salt. A variety of diaryl thioethers are synthesized under relatively mild reaction conditions with good chemoselectivity and functional group tolerance.