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Thieno[2,3-b]thiophene | CAS Number: 250-84-0

Catalog Number
ACM250840
Product Name
Thieno[2,3-b]thiophene
Structure
CAS Number
250-84-0
Synonyms
THIENO[2,3-B]THIOPHENE;1,6-Thiophthene;1,6-Dithiapentalene
Molecular Weight
140.23
Molecular Formula
C6H4S2
Purity
>97.0%(GC)
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1Antiproliferative activity of amino substituted benzo[b]thieno[2,3-b]pyrido[1,2-a]benzimidazoles explored by 2D and 3D cell culture system.

Perin N1, Bobanović K2, Zlatar I3, Jelić D3, Kelava V4, Koštrun S4, Marković VG4, Brajša K5, Hranjec M6.

Eur J Med Chem. 2017 Jan 5;125:722-735. doi: 10.1016/j.ejmech.2016.09.084. Epub 2016 Sep 26.

Benzimidazo[1,2-a]quinolines and benzo[b]thieno[2,3-b]pyrido[1,2-a]benzimidazoles with amino chains on the different positions have been evaluated by 2D and 3D assays on the human breast cancer cells. Pentacyclic derivatives were synthesized by microwave assisted amination to study the influence of the thiophene substructure on antitumor activity in comparison to tetracyclic analogues. The results obtained from 2D assay reveals that the antitumor activity is strongly dependent on the nature and position of amino chains. Read More

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Email:
Tel:1-201-478-8534
1-516-662-5404
Fax: 1-516-927-0118
Address: Suite 212, Waverly Plaza, 755 Waverly Avenue, Holtsville, NY 11742, USA