Dhawan U, Pan HA, Chu YH, Huang GS, Chen PC, Chen WL.
IEEE Trans Nanobioscience. 2016 Oct;15(7):704-712. doi: 10.1109/TNB.2016.2605686.Biomaterial design involves assessment of cellular response to nanotopography parameters such as shape, dimension of nanotopography features. Here, the effect of nanotopography alongside the in vivo factor, shear stress, on osteoblast cell behavior, is reported. Tantalum oxide nanodots of 50 or 100 nm diameter were engineered using anodized aluminum oxide as a template. Bare tantalum nitride coated silicon substrates were taken as control (flat). Read More