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Sulforhodamine b | CAS Number: 2609-88-3

Catalog Number
ACM2609883
Product Name
Sulforhodamine b
Structure
CAS Number
2609-88-3
IUPAC Name
2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]-5-sulfobenzenesulfonate
Synonyms
SULFORHODAMINE B, ACID FORM;XYLENE RED B;xanthylium,3,6-bis(diethylamino)-9-(2,4-disulfophenyl)-,hydroxide,innersalt;hydrogen 3,6-bis(diethylamino)-9-(2,4-disulphonatophenyl)xanthylium;SULFORHODAMINE B, ACID FORM, LASER GRADE;SULFORHODAMINE B ACID FORM, L
Molecular Weight
558.67
Exact Mass
558.14900
Molecular Formula
C27H30N2O7S2
Melting Point
>300ºC(lit.)
Purity
96%
Appearance
GREEN TO BROWN POWDER, CRYSTALS OR CRYSTALLINE POWDER OR red solid
InChIKey
IOOMXAQUNPWDLL-UHFFFAOYSA-N
H-Bond Donor
1
H-Bond Acceptor
8
Safty Description
S24/25
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1Dexamethasone induces docetaxel and cisplatin resistance partially through up-regulating Krüppel-like factor 5 in triple-negative breast cancer.

Li Z1,2,3, Dong J4, Zou T5, Du C2, Li S2, Chen C2, Liu R2, Wang K1,3.

Oncotarget. 2016 Dec 24. doi: 10.18632/oncotarget.14135. [Epub ahead of print]

PURPOSE: Dexamethasone (Dex), a glucocorticoid (GC), is used as a pretreatment drug in cancer patients undergoing chemotherapy. Dex functions by binding to the glucocorticoid receptor (GR) to prevent allergic reactions and severe chemotherapeutic side effects such as nausea and vomiting. However, the mechanisms by which Dex causes chemoresistance remain unknown.METHODS: We used docetaxel and cisplatin to treat triple-negative breast cancer (TNBC) cells with or without Dex and assessed cell proliferation using a sulforhodamine B colorimetric (SRB) assay. Read More

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Email:
Tel:1-201-478-8534
1-516-662-5404
Fax: 1-516-927-0118
Address: Suite 212, Waverly Plaza, 755 Waverly Avenue, Holtsville, NY 11742, USA