Wunderlich G1, Wendisch M, Aurich D, Runge R, Freudenberg R, Kotzerke J.
Nuklearmedizin. 2012;51(5):179-85. doi: 10.3413/Nukmed-0450-11-12. Epub 2012 Apr 12.Technetium radiopharmaceuticals are well established in nuclear medicine. Besides its well-known gamma radiation, (99m)Tc emits an average of five Auger and internal conversion electrons per decay. The biological toxicity of these low-energy, high-LET (linear energy transfer) emissions is a controversial subject. One aim of this study was to estimate in a cell model how much (99m)Tc can be present in exposed cells and which radiobiological effects could be estimated in (99m)Tc-overloaded cells. Read More