Kamat PK1, Kalani A, Givvimani S, Sathnur PB, Tyagi SC, Tyagi N.
Neuroscience. 2013 Nov 12;252:302-19. doi: 10.1016/j.neuroscience.2013.07.051. Epub 2013 Jul 31.High levels of homocysteine (Hcy), known as hyperhomocysteinemia are associated with neurovascular diseases. H2S, a metabolite of Hcy, has potent anti-oxidant and anti-inflammatory activities; however, the effect of H2S has not been explored in Hcy (IC)-induced neurodegeneration and neurovascular dysfunction in mice. Therefore, the present study was designed to explore the neuroprotective role of H2S on Hcy-induced neurodegeneration and neurovascular dysfunction. Read More