Bhana S1, O'Connor R1, Johnson J1, Ziebarth JD1, Henderson L1, Huang X2.
J Colloid Interface Sci. 2016 May 1;469:8-16. doi: 10.1016/j.jcis.2016.02.012. Epub 2016 Feb 3.Despite the advancement of photodynamic therapy and photothermal therapy, the ability to form compact nanocomplex for combined photodynamic and photothermal cancer therapy under a single near infrared irradiation remains limited. In this work, we prepared an integrated sub-100 nm nanosystem for simultaneous near infrared photodynamic and photothermal cancer therapy. The nanosystem was formed by adsorption of silicon 2,3-naphthalocyanine dihydroxide onto gold nanorod followed by covalent stabilization with alkylthiol linked polyethylene glycol. Read More