Massimo B1, Grignani G1, Giostra A1, Pagano M1, Ferrari S1, Elia BO1, Carnevale-Scianca F1, Aglietta M1, Pellerito RE1, Fagioli F1.
J Clin Oncol. 2011 May 20;29(15_suppl):10040.10040 Background: Bone metastatic patients with osteosarcoma have a very poor prognosis. Targeted radiation therapy has been pursued as a valid alternative and 153-Samarium ethylenediaminetetramethylene phosphonic acid (153Sm-EDTMP) has been investigated as a radiopharmaceutical agent selectively delivering radiation to osteoblastic skeletal lesions (Anderson PM et al. JCO 2002; 20:189-196).METHODS: Twenty-two osteosarcoma patients were treated with 153Sm-EDTMP at various dosages. Read More