Topotecan hydrochloride

• Catalog Number: ACM119413546
• Product Name: Topotecan hydrochloride
• CAS: 119413-54-6
• Category: Inhibitors
• Description: Topotecan Hydrochloride (SKF 104864A Hydrochloride) is a Topoisomerase I inhibitor with potent antineoplastic activities.
• Synonyms: 1,4-Di[4-(3-phenoxypropoxy)-2-butynyl]piperazine
• IUPAC Name: (19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride
• Molecular Weight: 457.91
• Molecular Formula: C23H24ClN3O5
• Canonical SMILES: CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O.Cl
• InChI: InChI=1S/C23H23N3O5.ClH/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20;/h5-8,27,30H,4,9-11H2,1-3H3;1H/t23-;/m0./s1
• InChI Key: DGHHQBMTXTWTJV-BQAIUKQQSA-N
• Melting Point: 213-218 °C
• Appearance: Light-yellow powder