(+/-)-Tetrahydro-2-furoic acid

• Catalog Number: ACM16874332-1
• Product Name: (+/-)-Tetrahydro-2-furoic acid
• CAS: 16874-33-2
• Category: Solvents
• Description: Tetrahydro-2-furoic acid is an organic compound with the formula HO2CC4H7O. It is a colorless oil. Tetrahydro-2-furoic acid is a useful pharmaceutical intermediate relevant to the production of several drugs, including Terazosin for the treatment of prostate enlargement and hypertension.
• Synonyms: tetrahydro-2-furoic acid
• IUPAC Name: oxolane-2-carboxylic acid
• Molecular Weight: 116.12
• Molecular Formula: C5H8O3
• Canonical SMILES: OC(=O)C1CCCO1
• InChI Key: UJJLJRQIPMGXEZ-UHFFFAOYNA-N
• Boiling Point: 243.2 °C at 760 mmHg
• Melting Point: 21ºC
• Flash Point: 113.2±18.9 °C
• Density: 1.3±0.1 g/cm³
• Solubility: Soluble in water
• Application: Reaction of tetrahydro-2-furoic acid with the hydrochloride salt of 3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]-propanenitrile provided alfuzosin, a drug for the treatment of benign prostatic hyperplasia (BPH).
• Assay: ≥98.0 %
• Color: Clear colorless to yellow to brown
• EC Number: 605-530-1
• Exact Mass: 116.04734
• Form: Liquid
• Hazard Codes: C:Corrosive
• Hazard Statements: H302-H314
• LogP: -0.61
• MDL Number: MFCD00022473
• PSA: 46.53
• Refractive Index: 1.48
• Vapor Pressure: 0.0±1.0 mmHg at 25°C
• WGK Germany: 3