N-(2-Mercaptopropionyl)glycine

• Catalog Number: ACM1953022
• Product Name: N-(2-Mercaptopropionyl)glycine
• CAS: 1953-02-2
• Category: Amino Acids
• Synonyms: Tiopronin
• Molecular Weight: 163.19
• Molecular Formula: CH3CH(SH)CONHCH2COOH
• Canonical SMILES: CC(S)C(=O)NCC(O)=O
• InChI: 1S/C5H9NO3S/c1-3(10)5(9)6-2-4(7)8/h3,10H,2H2,1H3,(H,6,9)(H,7,8)
• InChI Key: YTGJWQPHMWSCST-UHFFFAOYSA-N
• Melting Point: 98-100℃
• Application: N-(2-Mercaptopropionyl)glycine or Tiopronin has been used:; in the preparation of polyethylenimine (PEI)-coated gold microparticles (PEI-gold) for biolistic delivery of nucleic acids; to study the role of reactive oxygen species (ROS) at the reperfusion stage in in vivo isoflurane preconditioning-induced neuroprotection; as a ROS inhibitor to study its effect on lysophosphatidylcholine (LPC)-induced inflammasome activation
• Assay: ≥98% (TLC)
• Beilstein: 1859822
• Biochem Physiol Actions: N-(2-Mercaptopropionyl)glycine (NMPG) is a thiol compound associated with autoimmune hypoglycemia. It is a diffusible antioxidant and reduces the severity of colonic injury. NMPG also relieves myeloperoxidase activity and stimulates hypoxia-inducible factor-1 (HIF-1) - vascular endothelial growth factor (VEGF) pathway for ulcer healing.
• Color: white
• EC Number: 217-778-4
• Form: powder
• MDL Number: MFCD00004861
• NACRES: NA.26
• PubChem ID: 24897101
• Quality Level: 100
• Storage Temperature: 2-8℃