Catalog Number
ACM38304915-1
Category
Heterocyclic Organic Compound
Description
Minoxidil is a synthetic, anti-hypertensive drug that is used to treat high blood pressure. It was first introduced to the market in the early 1980s and has since become widely used in the treatment of hypertension. The drug is also used off-label to treat certain forms of hair loss, and is available in both topical and oral forms. Minoxidil is a potassium channel opener, meaning it works by widening blood vessels and allowing more blood to flow through them. This lowers blood pressure and helps to reduce the risk of heart attack and stroke.
Synonyms
6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide; 6-(1-Piperidinyl)pyrimidine-2,4-diamine 3-oxide; 2,4-Diamino-6-piperidinopyrimidine 3-N-oxide
IUPAC Name
3-Hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine
Molecular Formula
C9H15N5O
Canonical SMILES
C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O
InChI
InChI=1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2
InChI Key
ZIMGGGWCDYVHOY-UHFFFAOYSA-N
Boiling Point
351.7±45.0 °C at 760 mmHg
Melting Point
272-274 °C(lit.)
Solubility
Soluble in water (2.2 mg/ml), 100% ethanol (29 mg/ml), propylene glycol, acetone, DMSO (6.5 mg/ml), and methanol.
Appearance
White crystalline powder
Application
Minoxidil is a selective ATP dependent K+ (Kir6) channel activator
Stability
Stable at normal temperatures and pressures.
Supplemental Hazard Statements
H302-H315-H319-H335
Vapor Pressure
0.0±1.8 mmHg at 25°C