Megestrol acetate

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Catalog Number
ACM595335
Product Name
Megestrol acetate
Structure
Structure
CAS
595-33-5
Category
Inhibitors
Description
Megestrol acetate is a synthetic and orally active progesteronal agent. Megestrol acetate is effective as an appetite stimulant for wasting syndromes such as cachexia. Megestrol acetate decreases nuclear and cytosol androgen receptors human BPH tissue. Megestrol acetate has the potential for HIV study and downregulates autophagic catabolic pathway.
Synonyms
Megestrol acetate; [(8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate;
IUPAC Name
megestrol acetate
Molecular Weight
384.52
Molecular Formula
C24H32O4
Canonical SMILES
CC([C@@]1(OC(C)=O)CC[C@@]2([H])[C@]3([H])C=C(C)C4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O
Boiling Point
507.1ºC at 760mmHg
Melting Point
214ºC
Flash Point
218.5ºC
Density
1.15g/cm³
Appearance
Crystalline Solid
Storage
Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
Exact Mass
384.23000
Hazard Statements
Xn:Harmful
Safety Description
S22-S24/25
Shipping
Can be shipped at room temperature, where not in use may vary.
WGK Germany
3
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