Catalog Number
ACM667463958
Description
MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist, with IC50 of 44 μM (GSK-3) and 55 μM (CDK1/cyclin B), respectively. MeBIO is inactive on GSK-3β.
Synonyms
MeBIO; Me-BIO; Me BIO;
IUPAC Name
(2Z,3E)-6-Bromo-1-methylindirubin-3-oxime
Molecular Weight
370.206 g/mol
Molecular Formula
C17H12BrN3O2
Canonical SMILES
O=C(/C1=C2NC3=C(C\2=N/O)C=CC=C3)N(C)C4=C1C=CC(Br)=C4
InChI
InChI=1S/C17H12BrN3O2/c1-21-13-8-9(18)6-7-11(13)14(17(21)22)16-15(20-23)10-4-2-3-5-12(10)19-16/h2-8,19,23H,1H3/b16-14-,20-15+
InChI Key
JUKQKURGZYNHFN-NVVUQHMZSA-N
Shelf Life
>3 years if stored properly
Storage
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Drug Formulation
This drug may be formulated in DMSO
Elemental Analysis
C, 55.15; H, 3.27; Br, 21.58; N, 11.35; O, 8.64
HS Tariff Code
2934.99.03.00
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
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