Lacidipine

• Catalog Number: ACM103890784
• Product Name: Lacidipine
• CAS: 103890-78-4
• Category: Inhibitors
• Description: Lacidipine is an orally active and highly selective L-type calcium channel blocker that acts on smooth muscle calcium channels, primarily dilates peripheral arteries, reduces peripheral resistance, and has long-lasting anti-hypertensive activity. Lacidipine protects HKCs from apoptosis induced by ATP depletion and recovery by modulating the caspase-3 pathway. Lacidipine can be used in studies of hypertension, atherosclerosis and acute kidney injury (AKI).
• Synonyms: 3,5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(2-(3-(1,1-dimethylet;diethylester,(e)-hoxy)-3-oxo-1-propenyl)phenyl);MOTENS;GX-1048;GR-43659X;CALDINE;(E)-4-[2-[3-(1,1-DIMETHYLETHOXY)-3-OXO-1-PROPENYL]PHENYL]-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER;LACIPIL
• Molecular Weight: 455.54
• Molecular Formula: C₂₆H₃₃NO₆
• Canonical SMILES: O=C(C1=C(C)NC(C)=C(C(OCC)=O)C1C2=CC=CC=C2/C=C/C(OC(C)(C)C)=O)OCC
• Melting Point: 174-175°C
• Appearance: Solid
• Storage: Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
• Hazard Statements: Xn
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Supplemental Hazard Statements: H302
• Symbol: GHS07

Custom Q&A

What is the molecular formula of lacidipine?

The molecular formula of lacidipine is C26H33NO6.

What is the molecular weight of lacidipine?

The molecular weight of lacidipine is 455.5 g/mol.

What is the IUPAC name of lacidipine?

The IUPAC name of lacidipine is diethyl 2,6-dimethyl-4-[2-[(E)-3-[(2-methylpropan-2-yl)oxy]-3-oxoprop-1-enyl]phenyl]-1,4-dihydropyridine-3,5-dicarboxylate.

What is the InChIKey of lacidipine?

The InChIKey of lacidipine is GKQPCPXONLDCMU-CCEZHUSRSA-N.

What is the canonical SMILES of lacidipine?

The canonical SMILES of lacidipine is CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2C=CC(=O)OC(C)(C)C)C(=O)OCC)C)C.

What is the CAS number of lacidipine?

The CAS number of lacidipine is 103890-78-4.

What is the European Community (EC) number of lacidipine?

The European Community (EC) number of lacidipine is 638-759-0.

What is the ChEMBL ID of lacidipine?

The ChEMBL ID of lacidipine is CHEMBL460291.

What is the DSSTox Substance ID of lacidipine?

The DSSTox Substance ID of lacidipine is DTXSID1046429.

Is lacidipine currently FDA-approved?

No, lacidipine is not currently FDA-approved.