Isoliquiritigenin

• Catalog Number: ACM961295
• Product Name: Isoliquiritigenin
• CAS: 961-29-5
• Category: Inhibitors
• Description: Isoliquiritigenin is an anti-tumor flavonoid from the root of Glycyrrhiza uralensis Fisch., which inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μM.
• Synonyms: 2',4,4'-Trihydroxy-trans-chalcone
• IUPAC Name: (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
• Molecular Weight: 256.25
• Molecular Formula: C15H12O4
• Canonical SMILES: C1=CC(=CC=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O
• InChI: InChI=1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3+
• InChI Key: DXDRHHKMWQZJHT-FPYGCLRLSA-N
• Boiling Point: 504.0±42.0 °C
• Melting Point: 206-210 °C
• Density: 1.384±0.06 g/cm³
• Appearance: Yellow to orange powder
• Storage: 2-8 °C
• Complexity: 331
• Exact Mass: 256.07355886
• Isomeric SMILES: C1=CC(=CC=C1/C=C/C(=O)C2=C(C=C(C=C2)O)O)O
• Monoisotopic Mass: 256.07355886
• pKa: 7.50±0.35(Predicted)
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Source: PlantsLeguminosaeGlycyrrhiza uralensis Fisch.
• Topological Polar Surface Area: 77.8 Ų