Homobutein

• Catalog Number: ACM34000390
• Product Name: Homobutein
• CAS: 34000-39-0
• Category: Inhibitors
• Description: Homobutein a natural chalcones (can be found in many medicinal plants, fruits, vegetables, spices and nuts), is a potent HDACs/NF-κB dual inhibitor with IC50s of 190 and 38 μM, respectively. Homobutein also a chelator of iron (II and III) cations, shows various activities, including anticancer, anti-inflammatory, antiparasite and antioxidation.
• Synonyms: 2',4,4'-TRIHYDROXY-3-METHOXY CHALCONE;3-METHOXY-2',4',4-TRIHYDROXYCHALCONE;HOMOBUTEIN;(E)-2',4,4'-trihydroxy-3-methoxychalcone;3-O-methylbutein;HOMOBUTEIN WITH HPLC;HOMOBUTEIN hplc;(E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-2-propen-1-one
• IUPAC Name: (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one
• Molecular Weight: 286.3
• Molecular Formula: C16H14O5
• Canonical SMILES: COC1=C(C=CC(=C1)C=CC(=O)C2=C(C=C(C=C2)O)O)O
• InChI: InChI=1S/C16H14O5/c1-21-16-8-10(3-7-14(16)19)2-6-13(18)12-5-4-11(17)9-15(12)20/h2-9,17,19-20H,1H3/b6-2+
• InChI Key: BWFSBUVPIAIXKJ-QHHAFSJGSA-N
• Boiling Point: 523.8ºC at 760 mmHg
• Melting Point: 207-212ºC
• Flash Point: 197.6ºC
• Density: 1.369 g/cm³
• Appearance: Powder
• EC Number: 251-782-7
• Exact Mass: 286.08400
• H-Bond Acceptor: 5
• H-Bond Donor: 3