Catalog Number
ACM31694550-2
Product Name
Glycerol ethoxylate
Description
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation.
IUPAC Name
2-[2,3-bis(2-hydroxyethoxy)propoxy]ethanol
Molecular Weight
average Mn ~1000
degree of polymerization 20.4
Canonical SMILES
C(COCC(COCCO)OCCO)O
InChI
1S/C9H20O6/c10-1-4-13-7-9(15-6-3-12)8-14-5-2-11/h9-12H,1-8H2
InChI Key
UCYLROVJSUACAD-UHFFFAOYSA-N
Boiling Point
>200 °C (lit.)
Density
1.138 g/mL at 25 °C (lit.)
Application
Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. In addition to PEGylation, activated PEG derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity.
Covalently-Bonded Unit Count
1
EC Number
500-075-4;244-250-0
Exact Mass
224.125988g/mol
Features And Benefits
1. High quality products
2. Fast delivery
3. Additional products can be ordered, please contact us for details
Monoisotopic Mass
224.125988g/mol
Packaging
Packaging
250 mL in poly bottle
Refractive Index
n20/D 1.473 (lit.)
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