Gatifloxacin sesquihydrate

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Catalog Number
ACM180200662
Product Name
Gatifloxacin sesquihydrate
Structure
Structure
CAS
180200-66-2
Category
Inhibitors
Description
Gatifloxacin sesquihydrate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin sesquihydrate inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin sesquihydrate can be used to treat bacterial conjunctivitis in vivo.
Synonyms
AKOS NCG1-0010;1-CYCLOPROPYL-6-FLUORO-8-METHOXY-7-(3-METHYL-PIPERAZIN-1-YL)-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID;1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-8-METHOXY-7-(3-METHYLPIPERAZIN-1-YL)-4-OXO-3-QUINOLINECARBOXYLIC ACID;1-CYCLOPROPYL-6-FLUORO-1,4-
Molecular Weight
402.42
Molecular Formula
C19H22FN3O4.1.5(H2O)
Density
1.386 g/cm³
Appearance
Almost white to light yellow crystalline powder
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