Folic Acid

• Catalog Number: ACM59303-3
• Product Name: Folic Acid
• CAS: 59-30-3
• Category: Promotional Products
• Description: A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.
• Synonyms: Folic acid
• IUPAC Name: (2S)-2-[[4-[(2-Amino-4-oxo-3H-Pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
• Molecular Weight: 441.4
• Molecular Formula: C19H19N7O6
• Canonical SMILES: C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)NC(=N3)N
• InChI: InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
• InChI Key: OVBPIULPVIDEAO-LBPRGKRZSA-N
• Boiling Point: 552.35 °C
• Melting Point: 250 °C
• Density: 1.4704 g/cm³
• Appearance: Solid
• Storage: 2-8 °C
• Complexity: 767
• Exact Mass: 441.13968135
• Hazard Codes: Xn
• Isomeric SMILES: C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)NC(=N3)N
• MDL Number: MFCD00076077
• Monoisotopic Mass: 441.13968135
• Physical State: Solid
• pKa: 2.5
• Refractive Index: 1.6800
• Safety Description: 24/25
• Stability: Stable. Incompatible with heavy metal ions, strong oxidizing agents, strong reducing agents. Solutions may be light and heat sensitive.
• Topological Polar Surface Area: 209 Ų
• WGK Germany: 1

Custom Reviews

July 19, 2023

A vitamin

Folic acid has a positive effect on cell division and growth and the synthesis of nutrients.

Custom Q&A

How stable is folic acid?

Folic acid is stable to visible light, the activity is reduced by ultraviolet light, and the oxidative hydrolysis is accelerated by acid and alkali.

What is the acidity factor of folic acid?

pKa 2.5

What is the chemical structure of folic acid?

The structure of folic acid consists of a nystatin, which is conjugated to nystatin (nystatinyl) adjacent to p-aminobenzoic acid through a methylene bridge, and then combined with glutamic acid.

What is the EC number of folic acid?

200-419-0

What is the form of folic acid??

Yellow to orange crystalline powder

What is the InchI Key of folic acid?

OVBPIULPVIDEAO-LBPRGKRZSA-N

What is the refractive index of folic acid?

1.68

What is the specific optical rotation of folic acid?

20 º (c=1, 0.1N NaOH)

What is the synthesis of folic acid?

Folic acid can be synthesized by first synthesizing the pteridine nucleus and then condensing it with p-aminobenzoylglutamic acid to obtain folic acid, or crude folic acid can be obtained from the reaction of 2,4,5-triamino-6-hydroxypyrimidines, α,β-dibromopropanal, and p-aminobenzoylglutamic acid in acetic acid-sodium acetate buffer solution, which can be refined to obtain folic acid containing two molecules of water of crystallization. Similar to the latter Hop Chemicalbook method, p-aminobenzoylglutamic acid, trichloroacetone and 2,4,5-triamino-6-hydroxypyrimidine sulfate ([1603-20-7]) were cyclized for 6 h in the presence of sodium acetate and sodium metabisulfite, maintaining pH 3.4-3.6, and at a temperature of 36-40°C to give an orange-red folic acid precipitate

What is the way folic acid is absorbed?

Folic acid is absorbed in the body in two ways, actively and diffusely passively, and the site of absorption is mainly in the upper part of the small intestine.