Fmoc-Thr(Trt)-OH

• Catalog Number: ACM133180015
• Product Name: Fmoc-Thr(Trt)-OH
• CAS: 133180-01-5
• Category: Amino Acids
• Description: The side-chain Trt group can be selectively removed with 1% TFA in DCM containing 5% TIS, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support. This is an excellent derivative for synthesizing phosphothreonine-containing peptides and peptides modified at the threonine side-chain. The use of trityl-protected amino acids resulted in purer products than when standard t-Bu-protected amino acids were utilized.
• Synonyms: Fmoc-Thr(Trt)-OH, N-α-Fmoc-O-trityl-L-threonine
• Molecular Weight: 583.7
• Molecular Formula: C38H33NO5
• InChI: 1S/C38H33NO5/c1-26(44-38(27-15-5-2-6-16-27,28-17-7-3-8-18-28)29-19-9-4-10-20-29)35(36(40)41)39-37(42)43-25-34-32-23-13-11-21-30(32)31-22-12-14-24-33(31)34/h2-24,26,34-35H,25H2,1H3,(H,39,42)(H,40,41)/t26-,35+/m1/s1
• InChI Key: JARBLLDDSTVWSM-IJAHGLKVSA-N
• Melting Point: 70-85 ℃
• Solubility: Clearly soluble (1 mmole in 2 ml DMF)
• Application: Fmoc solid-phase peptide synthesis
• Assay: ≥78.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• Color: white to slight yellow to beige
• Form: powder
• Functional Group: hydroxyl
• HS Code: 2924 29 70
• Impurities: Water ≤ 1.5 %
• Quality Level: 200
• Storage Temperature: 15-25℃
• Type: Unlabeled Standard Amino Acids, Threonine (Thr)
• WGK Germany: WGK 2 obviously hazardous to water