Fmoc-Thr[GalNAc(Ac)3-α-D]-OH

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Catalog Number
ACM116783358-1
Product Name
Fmoc-Thr[GalNAc(Ac)3-α-D]-OH
Structure
Structure
CAS
116783-35-8
Category
Amino Acids
Description
The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine and TFA , making it completely compatible with standard protocols in Fmoc solid phase peptide synthesis. Removal of the acetyl protecting groups is best carried out by treatment of the peptidyl resin with methanolic ammonia prior to cleavage.
Synonyms
Fmoc-O-β-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-α-D-galactopyranosyl)-L-threonine
Molecular Weight
670.66
Canonical SMILES
CC(N[C@@H]1[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)O[C@@H]1O[C@H](C)[C@H](NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O)C(O)=O)=O
InChI
1S/C33H38N2O13/c1-16(27(31(40)41)35-33(42)44-14-25-23-12-8-6-10-21(23)22-11-7-9-13-24(22)25)45-32-28(34-17(2)36)30(47-20(5)39)29(46-19(4)38)26(48-32)15-43-18(3)37/h6-13,16,25-30,32H,14-15H2,1-5H3,(H,34,36)(H,35,42)(H,40,41)/t16-,26-,27+,28-,29+,30-,32+/m1/s1
InChI Key
OXLCJWGAUPPZQJ-ZNHCDWFHSA-N
Melting Point
178-183℃
Application
Peptide synthesis.
Assay
0.97
Form
solid
Functional Group
Fmoc
MDL Number
MFCD00171374
Optical Activity
[α]22/D +55.0°, c = 1% in chloroform
PubChem ID
329767565
Quality Level
100
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
-20℃
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