Fmoc-propargyl-Gly-OH

• Catalog Number: ACM198561078
• Product Name: Fmoc-propargyl-Gly-OH
• CAS: 198561-07-8
• Category: Amino Acids
• Description: Building block for the introduction by Fmoc SPPS. of an amino acid bearing an alkyne side chain. Such derivatives are useful tools for the synthesis of cyclic peptides by an alkyne-alkyne Glaser coupling, involving Cu(OAc)2/pyridine and heating to 60 ℃using microwaves.
• Synonyms: (S)-2-(Fmoc-amino)-4-pentynoic acid, Fmoc-L-2-propargylglycine
• Molecular Weight: 335.35
• Molecular Formula: C20H17NO4
• Canonical SMILES: OC(=O)[C@H](CC#C)NC(=O)OCC1c2ccccc2-c3ccccc13
• InChI: 1S/C20H17NO4/c1-2-7-18(19(22)23)21-20(24)25-12-17-15-10-5-3-8-13(15)14-9-4-6-11-16(14)17/h1,3-6,8-11,17-18H,7,12H2,(H,21,24)(H,22,23)/t18-/m0/s1
• InChI Key: DJGMNCKHNMRKFM-SFHVURJKSA-N
• Application: Peptide synthesis.
• Assay: ≥98.0% (HPLC)
• Beilstein: 9151699
• Color: white
• Form: powder or crystals
• Functional Group: Fmoc
• MDL Number: MFCD01075095
• NACRES: NA.26
• PubChem ID: 329747060
• Quality Level: 100
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 2-8℃
• Type: Unusual Amino Acids, Azide and Alkyne containing Amino Acids