Fmoc-NH-(PEG)10-CH2CH2COOH

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Catalog Number
ACM2101563453-1
Product Name
Fmoc-NH-(PEG)10-CH2CH2COOH
Structure
Structure
CAS
2101563-45-3
Category
Amino Acids
Description
Fmoc-NH-PEG10-CH2CH2COOH is a derivative of polyethylene glycol (PEG) that has been modified with a terminal carboxylic acid group and a base-labile 9-Fluorenylmethoxycarbonyl (Fmoc) protecting group. PEG is a biocompatible and highly hydrophilic polymer that is widely used in various biomedical applications due to its excellent solubility, low toxicity, and resistance to protein binding. The addition of a carboxylic acid group to PEG improves its water solubility and allows for conjugation to amino-containing molecules, such as peptides or proteins. The Fmoc protecting group is widely used in solid-phase peptide synthesis to protect the N-terminal amine group of amino acids from undesired side reactions during chain assembly.
Synonyms
1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34-undecaoxa-4-azaheptatriacontan-37-oic acid
IUPAC Name
3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Molecular Weight
751.8
Molecular Formula
C38H57NO14
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O
InChI
1S/C38H57NO14/c40-37(41)9-11-43-13-15-45-17-19-47-21-23-49-25-27-51-29-30-52-28-26-50-24-22-48-20-18-46-16-14-44-12-10-39-38(42)53-31-36-34-7-3-1-5-32(34)33-6-2-4-8-35(33)36/h1-8,36H,9-31H2,(H,39,42)(H,40,41)
InChI Key
NAILXQLIMFAMGQ-UHFFFAOYSA-N
Boiling Point
826.4±65.0 ℃at 760 mmHg
Flash Point
453.6±34.3 ℃
Density
1.2±0.1 g/cm3
Application
Fmoc-NH-PEG10-CH2CH2COOH has a wide range of applications in scientific experiments, including drug delivery, diagnostics, and imaging. Its hydrophilic and biocompatible nature makes it an ideal polymer for the synthesis of nanoparticles or micelles that can carry hydrophobic drugs and improve their solubility and bioavailability in biological systems. Its carboxylic acid group can also be used for the conjugation of various targeting ligands, such as antibodies or peptides, that can improve the specificity and efficiency of drug delivery.
Exact Mass
751.37793
Functional Group
Fmoc
LogP
0.15
MDL Number
MFCD28122954
Refractive Index
1.522
Storage Temperature
4 ℃
Type
Unusual Amino Acids, Pegylated Amino Acids & Special Linkers
Vapor Pressure
0.0±3.2 mmHg at 25℃
Please kindly note that our products are for research use only.

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